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KMID : 0614620100550040261
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Korean Journal of Gastroenterology
2010 Volume.55 No. 4 p.261 ~ p.265
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Calcium Polystyrene Sulfonate Induced Colonic Necrosis in Patient with Chronic Kidney Disease
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Lee Sung-Hoa
Kim Sung-Jung
Kim Go-Eun
Lee Woo-Jin
Hong Won-Ki
Baik Gwang-Ho
Choi Young-Hee
Kim Dong-Joon
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Abstract
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A 63-year-old woman was admitted due to right upper quadrant abdominal pain. She was going through hemodialysis due to end stage renal disease and taking calcium polystyrene sulfonate orally and rectally due to hyperkalemia. Colonoscopy showed a circular ulcerative mass on the proximal ascending colon. Biopsy specimen from the mass showed inflammation and necrotic debris. It also revealed basophilic angulated crystals which were adherent to the ulcer bed and normal mucosa. These crystals were morphologically consistent with calcium polystyrene sulfonate. She was diagnosed with calcium polystyrene phosphate induced colonic necrosis and improved with conservative treatment.
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KEYWORD
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Calcium polystyrene sulfonate, Colon, Necrosis, Hyperkalemia
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